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Friday, March 29, 2024

The big picture of cancer

For over a century, scientists have painstakingly worked to find the ultimate causes of cancers, hoping this could point to a cure for the disease. Many disparate agents are known to be associated with cancers: cigarette smoke, soot, asbestos, radiation, alcohol, chemicals, and others. But exactly how they lead to cancer is not entirely clear.

The cellular origins of cancer had been a mystery until the turn of the 21st century, when the inner molecular workings of a normal cell came into sharper focus. Genetic change (gene mutations) is now the most pervasive answer we hear from researchers. Errors in DNA duplication during cell division and DNA damaged by toxic substances, such as tobacco, alcohol, and UV light exposure, all have supporting medical evidence…

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